This page provides SIFT predictions for a list of chromosome positions and alleles.

Please provide your email address and input your data by using the 'upload file' option if input size is greater than 1000 chromosome locations.

Results are deleted after an hour, so please save them!

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PLEASE READ: If you do not receive a coding annototian and the variant has passed our coding filter, then our internal database had gene annotation discrepancies for that particular variant. Please convert variant coordinates to NCBI 37, or check by hand.

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User Input

Homo sapiens NCBI 36 Homo sapiens NCBI 37 Select Organism

Chromosome Coordinates
Paste in comma separated list of chromosome coordinates, orientation (1,-1) and alleles see [sample format]


-or-

Upload file containing chromosome coordinates and nucleotide substitutions (size limit: 1M)

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Enter your email address if you want the results through email :
Please check that your address is correct and your mailbox is not full.

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Output Options

Include the following fields in the output table
Ensembl Gene ID
Gene Name
Gene Description
Ensembl Transcript Status (Known / Novel)
Ensembl Protein Family ID
Ensembl Protein Family Description
Protein Family Size
Ka/Ks (Human-mouse)
Ka/Ks (Human-macaque)
OMIM Disease
Allele Frequencies (All Hapmap Populations - weighted average)
Allele Frequencies (CEU Hapmap population)

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